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📖 科研基础 -- 读文献、看教材

文献--肝癌空间转录组数据分析

Comprehensive analysis of spatial architecture in primary liver cancer Sci Adv. 2021 Dec 17 Doi: 10.1126/sciadv.abg3750. 简单摘要: 这是一篇资源型的文章,应该是第一篇较大规模的肝癌空间转录组测序文献。基于ST的所包含的空间信息,本...

Create: 2022-10-08 | Update: 2022-10-08 | Words: 2425 | 5 min | Lishensuo

文献--生信套路之肿瘤预后

【01】ccRCC与免疫浸润 标题:Landscape of immune cell infiltration in clear cell renal cell carcinoma to aid immunotherapy 期刊|日期:Cancer Science | 13 March 2021 1 第一次分亚群 TCGA 525样本(...

Create: 2023-04-17 | Update: 2024-04-17 | Words: 2251 | 5 min | Lishensuo

文献--ccRCC单细胞转录组

题目:Single-cell analyses of renal cell cancers reveal insights into tumor microenvironment, cell of origin, and therapy response 期刊 | 日期:PNAS | May 5, 2021 DOI:https://doi.org/10.107...

Create: 2023-04-17 | Update: 2024-04-17 | Words: 986 | 2 min | Lishensuo

文献--髓鞘脱失与再生模型小鼠snRNAseq数据分析

题目:Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination 期刊|日期:Cell Report | April 2023 DOI:https://doi.org/10.101...

Create: 2023-04-17 | Update: 2023-04-17 | Words: 1115 | 3 min | Lishensuo

文献--基于泛癌scRNAseq的T细胞图谱整合分析

题目:Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance 期刊|日期:nature medicine | 26 April 2023 DOI:https://doi.org/10.1038/...

Create: 2023-06-18 | Update: 2023-06-18 | Words: 2200 | 5 min | Lishensuo

文献--浆细胞(Plasma cells)在膀胱癌(Bladder cancer)中的预后分析

题目:The potential crosstalk between tumor and plasma cells and its association with clinical outcome and immunotherapy response in bladder cancer 期刊|日期:Journal of Translational Medicine | 03 May 2023 DOI:https://doi.org/10.11...

Create: 2023-06-23 | Update: 2023-06-23 | Words: 1402 | 3 min | Lishensuo

文献--机器学习模型预测药物肾毒性-1

题目:In Silico Prediction and Insights Into the Structural Basis of Drug Induced Nephrotoxicity 期刊 | 日期:05 January 2022 DOI: 10.3389/fphar.2021.793332 简括:建立机器学习模型的经典流程,值得注意的是包括化合物特征提取,模型建立/评价都...

Create: 2023-02-10 | Update: 2022-02-10 | Words: 737 | 2 min | Lishensuo

文献--机器学习模型预测药物肾毒性-2

题目:In silico prediction of potential drug-induced nephrotoxicity with machine learning methods 期刊 | 日期 : Journal of Applied Toxicology | 11 April 2022 简介:标准的机器学习模型分析流程,从数据收集到数据整理,从训练模型到评价模型。 1、...

Create: 2023-02-10 | Update: 2022-02-10 | Words: 1073 | 3 min | Lishensuo

文献--单细胞组学大模型之scGPT

文献: scGPT: toward building a foundation model for single-cell multi-omics using generative AI 时间:2024 Feb. (Published) 期刊:Nature Method DOI:https://doi.org/10.1038/s41592-0...

Create: 2024-09-29 | Update: 2024-09-29 | Words: 6652 | 14 min | Lishensuo

文献--单细胞组学大模型之scBERT

标题: scBERT as a large-scale pretrained deep language model for cell type annotation of single-cell RNA-seq data 期刊|日期:nature machine intelligence, 2022/09 DOI:https://doi.org/10.1038/s42256-0...

Create: 2024-11-09 | Update: 2024-11-09 | Words: 1150 | 3 min | Lishensuo
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