文献-流程图集锦
题目:Integrated analysis to identify the prognostic and immunotherapeutic roles of coagulation-associated gene signature in clear cell renal cell carcinoma 期刊:Frontiers in Immunology https://doi.org/10.3389/fimmu.2023.1107419
题目:Integrated analysis to identify the prognostic and immunotherapeutic roles of coagulation-associated gene signature in clear cell renal cell carcinoma 期刊:Frontiers in Immunology https://doi.org/10.3389/fimmu.2023.1107419
A network approach reveals driver genes associated with survival of patients with triple-negative breast cancer April 19, 2021; IF=5.4 https://doi.org/10.1016/j.isci.2021.102451 1、WGCNA分析 (1)对773个来自TCGA的BRCA(包括92个TNBC)的31338个基因表达...
Network Pharmacology-Based Analysis on the Potential Biological Mechanisms of Sinisan Against Non-Alcoholic Fatty Liver Disease(四逆散–非酒精性脂肪肝) 27 August 2021 Front Pharmacol, IF=5.8 DOI: 10.3389/fphar.2021.693701 分析思路 文章的流程图 1、数据收集 1.1 TCM数据...
Network-based prediction of drug combinations Nature communication 2019 / 03 IF=15 https://doi.org/10.1038/s41467-019-09186-x 文章使用数据 1、PPI high-quality protein-protein interactions (PPIs) 原文说有243,603 PPIs connecting 16,677 unique proteins ,但是根据文章附件链接只有217160 PPIs, 涉及15970...
本次的两篇文章属于同一团队,第一篇文章侧重提出计算方法;第二篇文章侧重于应用方法,发现生物学规律 Paper1:提出方法 SIGN: similarity identification in gene expression Bioinformatics 2019 / 2 IF...
1、算法简介 1.1 关系拆解 通过计算方法( 例如相关性Pearson correlation, 互信息mutual information等)构建的相互关系网络中,节点两两之间...
(1)Computational Drug Repurposing for Alzheimer’s Disease Using Risk Genes From GWAS and Single-Cell RNA Sequencing Studies https://www.frontiersin.org/articles/10.3389/fphar.2021.617537/full Front Pharmacol, 2021/06, IF 5.81 (2)gene...
Discovery of drug mode of action and drug repositioning from transcriptional responses August 2, 2010 | PNAS | IF=11.2 10.1073/pnas.1000138107 1、合并PRL cMap 1309种化合物作用于5种细胞系的6100个干扰转录组的差异基因结果。对于同一种化合...
DrugCombDB: a comprehensive database of drug combinations toward the discovery of combinatorial therapy Nucleic Acids Research | 2020 | IF=17 1、数据收集 (1)HTS(high-throughput screening)高通量筛选技术可用于快速...
A single-cell analysis of breast cancer cell lines to study tumour heterogeneity and drug response Nature Communications | 31 March 2022 DOI: https://doi.org/10.1038/s41467-022-29358-6 这篇文章对来自32个乳腺癌细胞系的35276个细胞进行了单细胞转录组测序(Drop-seq),...